Candace S Hayes Selected Research

Ornithine Decarboxylase (Decarboxylase, Ornithine)

3/2014	Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment.
3/2014	Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites.
9/2011	A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development.
1/2011	Elevated epidermal ornithine decarboxylase activity suppresses contact hypersensitivity.
4/2008	Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes.
8/2007	Polyamine-mediated regulation of protein acetylation in murine skin and tumors.
8/2006	Tip60 protein isoforms and altered function in skin and tumors that overexpress ornithine decarboxylase.
1/2005	Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (-)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice.

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Candace S Hayes Research Topics

Disease

9	Neoplasms (Cancer) 01/2015 - 01/2005
6	Carcinogenesis 03/2014 - 01/2005
1	Neoplasm Metastasis (Metastasis) 01/2015
1	Inflammation (Inflammations) 09/2011
1	Hyperplasia 09/2011
1	Wounds and Injuries (Trauma) 09/2011
1	Contact Dermatitis (Eczema, Contact) 01/2011
1	Neuroblastoma 12/2008
1	Ataxia Telangiectasia (Louis Bar Syndrome) 04/2008

Drug/Important Bio-Agent (IBA)

9	PolyaminesIBA 03/2014 - 01/2005
8	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 03/2014 - 01/2005
4	EnzymesIBA 03/2014 - 08/2007
3	Eflornithine (Ornidyl)FDA Link 03/2014 - 12/2008
3	Proteins (Proteins, Gene)FDA Link 09/2011 - 08/2006
2	Transcription Factors (Transcription Factor)IBA 08/2007 - 08/2006
2	Protein Isoforms (Isoforms)IBA 08/2007 - 08/2006
1	FibrinIBA 01/2015
1	Thrombin FDA Link 01/2015
1	Dabigatran FDA Link 01/2015
1	ArginaseIBA 01/2015
1	Proteinase-Activated ReceptorsIBA 01/2015
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2015
1	Thromboplastin (Tissue Factor)IBA 01/2015
1	afimoxifene (hydroxytamoxifen)IBA 03/2014
1	Oxidoreductases (Dehydrogenase)IBA 03/2014
1	anthraceneIBA 03/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2014
1	Dexamethasone (Maxidex)FDA LinkGeneric 09/2011
1	CarcinogensIBA 09/2011
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 09/2011
1	CREB-Binding ProteinIBA 08/2007
1	Messenger RNA (mRNA)IBA 08/2006
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 08/2006
1	TeaIBA 01/2005
1	PolyphenolsIBA 01/2005
1	Drinking WaterIBA 01/2005

Therapy/Procedure

1	Oral Administration 01/2015
1	Therapeutics 03/2014
1	Neoadjuvant Therapy 03/2014